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KMID : 0356920070530010145
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Korean Journal of Anesthesiology
2007 Volume.53 No. 1 p.145 ~ p.149
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Delayed Recovery of Neuromuscular Blockade by Rocuronium in a Patient with Charcot-Marie-Tooth Disease
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Cheong Yong-Kwan
Lee Cheol
Son Yong
Song Yoon-Kang
Kim Tai-Yo
Kim Dea-Jung
O Se-Ri
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Abstract
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Charcot-Marie-Tooth disease, which is also known as hereditary motor and sensory neuropathy, is a heterogenous group of inherited diseases of the peripheral nerve. The spectrum of severity varies from asymptomatic individuals to those with severe limb abnormalities requiring corrective surgery. We report two brothers who had previously been diagnosed with Charcot-Marie- Tooth disease 3 years earlier and were scheduled to undergo a correction osteotomy of both feet under general anesthesia. General anesthesia was induced with propofol 2 mg/kg, rocuronium 0.8 mg/kg and was maintained with O2-N2O-Sevoflurane. The younger brother showed no delay in recovery of the neuromuscular blockade but the elder brother showed a delay. (Korean J Anesthesiol 2007; 53: 145∼9)
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KEYWORD
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Charcot-Marie-Tooth disease, neuropathy, rocuronium.
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